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primary human pulmonary arterial endothelial cells (paecs) cc-2530  (Lonza)


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    Lonza primary human pulmonary arterial endothelial cells (paecs) cc-2530
    Primary Human Pulmonary Arterial Endothelial Cells (Paecs) Cc 2530, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary human pulmonary arterial endothelial cells (paecs) cc-2530/product/Lonza
    Average 90 stars, based on 1 article reviews
    primary human pulmonary arterial endothelial cells (paecs) cc-2530 - by Bioz Stars, 2026-02
    90/100 stars

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    A , Relative mRNA expression profiles of cGAS-STING pathway genes ( cGAS, STING, IRF3, IRF7, IFIT1, IFIT2, IFIT3 and CXCL10 ) in total lung tissues from PH patients and healthy controls (n=5-11). B , Protein expression levels of STING in the total lung tissues of PH patients and healthy controls (n=4). C , Representative colocalization staining of STING (red), vWF (red) and α-SMA (green) in pulmonary arteries of healthy controls and PH patients (n=4), Scale bar=20μm. D , Protein expression levels of STING in <t>PAECs</t> and PASMCs (n=4). E, Relative mRNA expression of STING in PAEC exposure to 1% O 2 hypoxia for 24h (n=4). F, Relative mRNA expression of Sting in lung microvascular <t>endothelial</t> cells from hypoxia and SuHx mouse PH models (n=4). Data are presented as mean ± SEM. * P <0.05, ** P <0.01, *** P <0.01. Statistical analysis was done using Unpaired t test for A, B, D, and E. Statistical analysis was done using One-way ANOVA for F.
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    A , Relative mRNA expression profiles of cGAS-STING pathway genes ( cGAS, STING, IRF3, IRF7, IFIT1, IFIT2, IFIT3 and CXCL10 ) in total lung tissues from PH patients and healthy controls (n=5-11). B , Protein expression levels of STING in the total lung tissues of PH patients and healthy controls (n=4). C , Representative colocalization staining of STING (red), vWF (red) and α-SMA (green) in pulmonary arteries of healthy controls and PH patients (n=4), Scale bar=20μm. D , Protein expression levels of STING in <t>PAECs</t> and PASMCs (n=4). E, Relative mRNA expression of STING in PAEC exposure to 1% O 2 hypoxia for 24h (n=4). F, Relative mRNA expression of Sting in lung microvascular <t>endothelial</t> cells from hypoxia and SuHx mouse PH models (n=4). Data are presented as mean ± SEM. * P <0.05, ** P <0.01, *** P <0.01. Statistical analysis was done using Unpaired t test for A, B, D, and E. Statistical analysis was done using One-way ANOVA for F.
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    Image Search Results


    A , Relative mRNA expression profiles of cGAS-STING pathway genes ( cGAS, STING, IRF3, IRF7, IFIT1, IFIT2, IFIT3 and CXCL10 ) in total lung tissues from PH patients and healthy controls (n=5-11). B , Protein expression levels of STING in the total lung tissues of PH patients and healthy controls (n=4). C , Representative colocalization staining of STING (red), vWF (red) and α-SMA (green) in pulmonary arteries of healthy controls and PH patients (n=4), Scale bar=20μm. D , Protein expression levels of STING in PAECs and PASMCs (n=4). E, Relative mRNA expression of STING in PAEC exposure to 1% O 2 hypoxia for 24h (n=4). F, Relative mRNA expression of Sting in lung microvascular endothelial cells from hypoxia and SuHx mouse PH models (n=4). Data are presented as mean ± SEM. * P <0.05, ** P <0.01, *** P <0.01. Statistical analysis was done using Unpaired t test for A, B, D, and E. Statistical analysis was done using One-way ANOVA for F.

    Journal: bioRxiv

    Article Title: STING contributes to pulmonary hypertension by targeting the interferon and BMPR2 signaling through targeting F2RL3

    doi: 10.1101/2024.02.20.578386

    Figure Lengend Snippet: A , Relative mRNA expression profiles of cGAS-STING pathway genes ( cGAS, STING, IRF3, IRF7, IFIT1, IFIT2, IFIT3 and CXCL10 ) in total lung tissues from PH patients and healthy controls (n=5-11). B , Protein expression levels of STING in the total lung tissues of PH patients and healthy controls (n=4). C , Representative colocalization staining of STING (red), vWF (red) and α-SMA (green) in pulmonary arteries of healthy controls and PH patients (n=4), Scale bar=20μm. D , Protein expression levels of STING in PAECs and PASMCs (n=4). E, Relative mRNA expression of STING in PAEC exposure to 1% O 2 hypoxia for 24h (n=4). F, Relative mRNA expression of Sting in lung microvascular endothelial cells from hypoxia and SuHx mouse PH models (n=4). Data are presented as mean ± SEM. * P <0.05, ** P <0.01, *** P <0.01. Statistical analysis was done using Unpaired t test for A, B, D, and E. Statistical analysis was done using One-way ANOVA for F.

    Article Snippet: Human pulmonary artery endothelial cells (PAECs) were purchased from Promcell (C-12241).

    Techniques: Expressing, Staining